Constant fatigue and 'brain fog' - clue found in DNA
British scientists have discovered epigenetic changes in DNA linked to chronic fatigue syndrome. Researchers at the University of East Anglia identified similar mechanisms in five conditions, including long Covid and multiple sclerosis. The discovery could aid in diagnosis and treatment.
Scientists from the University of East Anglia (UK) have found epigenetic changes in DNA that may be linked to chronic fatigue syndrome (CFS). The study, reported by the Daily Mail, revealed that these changes affect energy production in the body, which could explain key symptoms — constant exhaustion, sleep problems, pain, dizziness, and 'brain fog'. Similar epigenetic changes were found in four other conditions: long Covid, multiple sclerosis, rheumatoid arthritis, and post-traumatic stress disorder. Although the genes involved in each case are different, the mechanism is similar — it is related to energy production and chronic exhaustion. Researchers believe that common mechanisms could lead to a unified treatment approach. The article features the story of 35-year-old Emma Slack from Newcastle, who was diagnosed with CFS only in 2017, nine years after her first symptoms appeared. Initially, doctors mistakenly attributed her condition to anxiety. Despite her illness, she earned a PhD in epidemiology. Scientists hope that further study of epigenetic changes will help create a blood test for faster diagnosis. Experts note that the mechanisms of the disease are not well understood, and it is too early to talk about ready-made therapies.