Back to the Twenties: Human Skin Treatment Rejuvenates Skin

South Korean researchers have developed a skin rejuvenation treatment using human skin tissue from deceased donors, known as 'Elravie Re2O'. It aims to stimulate skin regeneration rather than temporarily hiding wrinkles. The treatment uses processed human dermal matrix that preserves collagen, elastin, and hyaluronic acid. It has been used in South Korea since 2024 and has not yet received FDA approval, with potential risks of immune reactions.

South Korean researchers have developed an innovative anti-aging treatment using human skin tissue from deceased donors to restore skin vitality and a youthful appearance. The treatment, called 'Elravie Re2O'—short for 'Return to the Twenties'—aims to stimulate skin regeneration rather than temporarily hiding wrinkles. The concept involves using skin samples that undergo laboratory processing to remove human cells and genetic material while preserving structural components like collagen, elastin, and hyaluronic acid. The resulting substance, known as 'processed human dermal matrix', acts as a natural scaffold that helps skin cells adhere and grow. Some dermatology clinics in South Korea began using the treatment in late 2024, with reports of improved skin elasticity, hydration, and reduced wrinkles. Although limited use has started in the United States, it has not yet received FDA approval, and the developing company aims to officially launch it in the US market by 2027. Experts warn of potential risks such as immune reactions or infection, though these are low with modern screening and sterilization procedures.